Observations on the Phagocytosis of the Pneumococcus by Human Whole Blood

Studies on the Action of Sulfapyridine on Pneumococci.

In previous studies (1) it was shown that sulfanilamide in the concentrations ordinarily attained in therapy, exerts a marked bacteriostatic action on Type III pneumococcus when added to human blood in vitro or when found in the blood of patients with pneumonia after treatment. There was no appreciable bactericidal action except in some instances when large concentrations of the drug were used....

Enhancement of Toxic Substances Clearance from Blood Equvalent Solution and Human Whole Blood through High Flux Dialyzer by 1 MHz Ultrasound

Background: Hemodialysis is a process of removing waste and excess fluid from blood when kidneys cannot function efficiently. It often involves diverting blood to the filter of the dialysis machin to be cleared of toxic substances. Fouling of pores in dialysis membrane caused by adhesion of plasma protein and other toxins will reduce the efficacy of the filtre.Objective: In This study, the infl...

Studies on Natural Immunity to Pneumococcus Type Iii Iv. Observations on a Non-type Specific Humoral Factor Involved in Resistance to Pneumococcus Type Iii By

Experimental evidence presented in Paper III* indicates that removal and destruction of both rabbit virulent and avirulent strains of Pneumococcus Type III in the normal animal are brought about by the same means, namely, the phagocytic cells of the body, provided the integrity of the capsule becomes impaired. It leaves unanswered, however, the interesting q~aestion as to whether this phagocyto...

the Resistance to a Specific Hemolysin of Human Erythrocytes in Health and Disease

1. Phagocytosis of pneumococci in vitro runs parallel with phagocytosis in vivo. 2. Virulence depends not only on resistance to phagocytosis, but also on the ability to grow in the body of the animal. 3. The biological reaction of the pigeon to pneumococcus infection does not differ from that of the mouse. 4. The "immunity" of the pigeon to pneumococcus infection is due to its normal high tempe...

OBSERVATIONS ON THE PHAGOCYTOSIS OF THE PNEUMO- COCCUS BY HUMAN WHOLE BLOOD I. rIME NORMAl, PHAGOCYTIC TITRE, AND THE ANTI-PIIAGOCYTIC EFFECT OF THE SPECIFIC SOLUBLE SUBSTANCE BY HUGH